Rabbit Anti CRADD Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 50% glycerol, pH7.3 This antibody has been affinity purified.
More Details:
- Host: Rabbit
- Species: Human,Mouse
- Target: CRADD
- Clonality: Polyclonal
- Purity: Affinity Purified
- Immunogen: Recombinant fusion protein of human CRADD (NP_003796.1).
- Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.
This product can be used in analytical tools such as Western Blot.
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For research use only.